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High seperation and purification

LEXosome is an exosome as a key active ingredient in BotanicExo,

by culturing stem cell of plant, 'Lithospermum Erythororhizon'.


And the particle size of LEXosome is 50 to 200(nm), which can pass through the cytoplasm. 



NTA (Nanoparticle Tracking Analysis)

TEM (Transmission Electron Microscopy)

LEXosome l Delivery to Cell

After staining LEXosome with green fluorescent marker, the extent of fibroblast infiltration was examined.

LEXosome infiltrated into the cytoplasm around the nucleus dyed with DAPI without destroying the cells.



PKH67 : Cell membrane fluorescent labeling dye

DAPI : Cell nucleus staining dye

DDP

LEXosome l Wound Healing

At Day 1 of wound treatment, the wound recovery rates were as follws:



untreated control (0) was 12.1%, LEXosome at 1x109 particles/ml were 68.8%. Wound healing in fibroblasts improved by 232% with the application of LEXosome.

LEXosome l Anti-inflammatory

LEXosome hinders the transformation of macrophages into a dendritic shape induced by LPS.

Macrophages transformed into a dendritic shape by inflammatory substance LPS, restored its own shape.

LEXosome l Collagen Synthesis

LEXosome promotes the production of collagen type I, which acts as a crosslink in the dermal layer.

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